The Koschmann Lab

The Koschmann lab is studying the molecular mechanisms by which mutations in pediatric High-Grade Glioma (HGG) and Diffuse Intrinsic Pontine Glioma (DIPG) can be therapeutically targeted. The Koschmann Lab’s work in precision medicine pushes the boundaries of targeted therapies and precision diagnostics for children diagnosed with these brain tumors. Through highly collaborative basic, translational, and clinical research, the Koschmann Lab strives towards improving outcomes and providing hope for children fighting these devastating diseases.


Dr. Carl Koschmann

Dr. Koschmann came to the University of Michigan on a fellowship and established a research lab intent on improving the measurement and success of therapies for the most aggressive forms of pediatric brain tumors.

Standard cancer therapies like chemotherapy, radiation, and surgery can be detrimental to a child’s developing brain, requiring a more novel approach to treatment. As a result, Dr. Koschmann practices precision medicine. Using an algorithm developed out of the UM Brain Tumor Precision Medicine conference, Dr. Koschmann can build a targeted treatment regimen based on the sequencing of the patients’ brain tumor, providing them with optimized care. 



Lab Members


Amy Bruzek, M.D.

Neurosurgery Resident Researcher


Rodrigo Cartaxo, Ph.D.

Post-Doctoral Research Fellow


Micah Harris, B.S.

Research Technician


Zac Miklja, B.S.

Research Technician


Ash Muruganand

Undergraduate Student Researcher


Ramya Ravindran, B.S., M.S.

Research Technician


Mary Reiber

Undergraduate Student Researcher


Kallen Schwark, B.S.

M.D. / Ph.D. Student Researcher


Karthik Ravi

Undergraduate Student Researcher


Kyle Wierzbicki

Undergraduate Student Researcher


Vivek Yadav, Ph.D.

Research Investigator


Positions Available

We are looking for research technicians, postdoctoral fellows and undergraduate and graduate students to join our team with experience and/or interest in the following areas:

  • Neuroscience and/or oncology laboratory

  • Animal modeling

  • Cancer computational/bioinformatics

  • Experimental therapeutics/drug testing

Send a cover letter describing your specific interest and relevant qualifications and skills, along with your CV and the names and contact information for references to: