We are thankful beyond words

for the generous support from our donors and the University of Michigan Department of Pediatrics.

Our endless gratitude is matched only by our eternal optimism. With the help of our donors and visionary people like you, all working together, we will find the answers and the cures.

 

Chad Carr Pediatric Brain Tumor Center

The Chad Carr Pediatric Brain Tumor Center was established in 2018 through the efforts of the Chad Carr family and a few dedicated volunteers who, along with U-M leadership, envisioned what it would take to make U-M a leader in the care, treatment and cure of pediatric brain tumors, especially DIPG. The first major gift establishing a concerted pediatric brain tumor research endeavor at U-M came in early 2015, and the initiative’s first two projects were funded in 2016. In 2017, the endeavor picked up speed with the formal introduction of the annual Proof of Principal Research Collaboration (P3RC) Award.  Work in the Koschmann lab and trial now enrolling children with high-grade glioma and DIPG at the University of Michigan were selected for funding through this award process.

NIH/NINDS

The mission of the NINDS branch of the NIH is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease. To support this mission, NINDS: Supports and performs basic, translational, and clinical neuroscience research. Funds and conducts research training and career development programs to increase basic, translational and clinical neuroscience expertise and ensure a vibrant, talented, and diverse work force. And they promotes the timely dissemination of scientific discoveries and their implications for neurological health to the public, health professionals, researchers, and policy-makers. Dr. Koschmann was awarded an NIH/NINDS K08 award (2016-2021) for this work studying the role of the histone chaperone protein ATRX in pediatric high-grade glioma.

hyundai hope on wheels

Hyundai supports the finest minds in pediatric cancer research…the concerned physicians and dedicated research professionals at the member institutions of the Children’s Oncology Groups of America. They look for ways of preventing cancer, improving quality of life and survival. These doctors and research scientists are the human faces of hope to the children and families facing a pediatric cancer diagnosis. Through its collaborative research, the group improves cure rates at a much faster pace than individual institutions. Grant winners are determined by a scientific review panel of physicians. Dr. Koschmann was awarded the Hyundai Hope Scholar Award for work targeting PDGFR-mutated pediatric high-grade glioma in 2017.

The Chad Tough Foundation

The mission of The ChadTough Foundation is to fund research and raise awareness for Pediatric Brain Tumors with an emphasis on Diffuse Intrinsic Pontine Glioma (DIPG). DIPG presents a great challenge, it is an extremely difficult and complex disease. We believe a cure will come from talented, passionate people working collaboratively. It will come from “Thinking outside the Box” and taking some risks. It will come from small breakthroughs happening in many different areas of medicine. The ChadTough Foundation is committed to funding this work.  The ChadTough Foundation has supported the Koschmann lab through fundraising and support of the Chad Carr PBTC and directly with the contribution of major two year grant to support collaborative work on improving therapies for DIPG in the Koschmann and Venneti labs.

catching up with jack

Started by Brady and Katie Fineske, Catching up with Jack is a charitable fund focused on helping find a cure through research dollars, and helping other families faced with a pediatric cancer diagnosis.  The Fund is inspired by their son, Jack, who was treated at Mott Hospital for medulloblastoma, and passed away in 2015.  Catching Up With Jack harnesses Jack’s incredible courage, faith, and sense of community.  Catching Up with Jack has been a huge supporter of the Koschmann lab, and some of the proceeds from the 2017 and 2018 Catching Up with Jack 5K were donated to pay for multiple pieces of innovative equipment to allow for the in-house integration of tumor sequencing in the Koschmann lab to help advance new therapies for children with high-risk brain tumors.

prayers from maria.PNG

Prayers From MAria / Kasey MIKES GRANT

Ed and Megan started Prayers from Maria - Children’s Glioma Cancer Foundation that is dedicated to funding global research into the causes, prevention, treatments and cure for childhood brain tumors, known as gliomas. Because childhood gliomas are grossly under funded, the McNamara family is diligently working to make a difference by raising public awareness and bringing hope to children and their families who live with this disease. To date, the Foundation has awarded hundreds of thousands of dollars in grants to desperately needed research. The Koschmann lab was awared the Kasey Mikes Grant from 2019-2021 for work with precision medicine therapy and CSF tDNA monitoring of H3K27M-mutant DIPG.

u can-cer vive.PNG

U CAN-CER VIVE

Founded by siblings, Ryan and Kelley LaFontaine, it is the ongoing mission of the U CAN-CER VIVE Foundation to provide vital funding and support for local cancer research grants. Upon becoming an official nonprofit foundation in February 2016, U CAN-CER VIVE has raised over $1,000,000. The Koschmann lab was awarded a grant from the U CAN-CER VIVE Foundation from 2019-2021 for work to improved targeted therapies for PDGFR-driven DIPG and high-grade gliomas.

mircore.png

MirCORE

miRcore is a non-profit organization that builds funds for microgrants, supporting innovative genetic research by integrating the efforts of scientists, doctors, and the public. One of miRcore’s aims is to be guided, in a literal sense, by the public interest. mirCore funded a micro grant in the Koschmann lab in 2018 which funds work looking at genomics of spinal fluid tumor DNA (tDNA). Additionally, multiple miRcore graduates are currently working in the Koschmann lab, helping to build computational pipelines for sequencing tDNA.